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The age of liver transplant recipients has increased steadily over the last 15 years in the United States and Europe (Fig. 1A,B).For instance, the proportion of liver transplant recipients aged 65 or more increased from 9% in 2002 to 20% in 2017 in the United States. 2 In the Eurotransplant area, there has been a 16% increase in the number of liver transplant recipients aged 65 years or more …
Jan 17, 2019 · Antigen or activator was targeted to CD169 + MØs via a synthetic glycan on liposomes. Targeting of antigen alone promoted expansion of CD4 + T cells. CD169 + MØs were selectively activated by targeted liposomes with a TLR7 agonist. Targeting of antigen to activated CD169 + macrophages biased priming of CD8 + T cells
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